When you get to the point where you dread getting out of bed in the morning, you dread going to work, and you would rather run over a skunk with your bicycle than have to be civil to your boss for one more day -- well, that's the time you might want to be thinking of change.
Okay, so change ain't so great sometimes. It may mean less pay, more travel time, maybe a move to a different city or state, but wouldn't that be a whole lot better than doing something you really can't stand anymore? Do you really have enough time left on this planet to just "put up with" a whole lot of goat poop?
Clock's ticking! You decide! As for me, I don't mind change. I prefer $10s and $20s, but change works just as well.